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NEUROINFLAMMATORY MECHANISMS IN ALZHEIMER?S DISEASE IBD

BIRKHäUSER
08 / 2001
9783764360740
Inglés

Sinopsis

Basic Research Overview.- Cellular and molecular mechanisms of Alzheimer?s disease inflammation.- Clinical Research Overview.- Anti-inflammatory agents as possible protective factors for Alzheimer?s disease: Analysis of relevant epidemiological studies.- Topics of Special Interest.- Role and regulation of early complement activation products in Alzheimer?s disease.- Complement mediator systems in Alzheimer?s disease.- Amyloid ? peptide interactions with the classical pathway of complement.- Physiology and biochemistry of the interleukin-6 receptor complex. Implications for CNS disorders and Alzheimer?s disease.- Interactions of ?2-macroglobulin and amyloid ? peptide.- Proinflammatory actions of derivatives of the ? amyloid precursor protein.- The involvement of glial cell-derived reactive oxygen and nitrogen species in Alzheimer?s disease.- The role of cyclooxygenase in Alzheimer?s disease neurodegeneration.- Microglia.- Neurons.- The gero-inflammatory manifold.

PVP
119,09